Human ileal bile acid transporter gene ASBT (SLC10A2) is transactivated by the glucocorticoid receptor

Background: Patients with Crohn’s disease suffer from intestinal bile acid malabsorption. Intestinal bile acid absorption is mediated by the apical sodium dependent bile acid transporter ASBT/IBAT (SLC10A2). In rats, ASBT is induced by glucocorticoids. Aims: To study whether human ASBT is activated...

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Main Authors: Jung, D, Fantin, A C, Scheurer, U, Fried, M, Kullak-Ublick, G A
Format: Artigo
Jezik:Inglês
Izdano: Copyright 2004 by Gut 2004
Teme:
Inflammatory Bowel Disease
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773940/
https://ncbi.nlm.nih.gov/pubmed/14684580
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