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Secreted Wnt Modulators in Symptomatic Aortic Stenosis

BACKGROUND: Valve calcification and inflammation play key roles in the development of aortic stenosis (AS). The Wnt pathways have been linked to inflammation, bone metabolism, angiogenesis, and heart valve formation. We hypothesized that soluble Wnt modulators may be dysregulated in symptomatic AS....

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Detalhes bibliográficos
Main Authors: Askevold, Erik Tandberg, Gullestad, Lars, Aakhus, Svend, Ranheim, Trine, Tønnessen, Theis, Solberg, Ole G., Aukrust, Pål, Ueland, Thor
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540657/
https://ncbi.nlm.nih.gov/pubmed/23316316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.112.002261
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