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Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy

The Wingless (Wnt) pathway has been implicated in the pathogenesis of dilated cardiomyopathy (DCM). To explore the role of Wnt modulators Wnt5a and sFRP3 in DCM patients we analyzed the expression of Wnt5a and sFRP3 in plasma and myocardium of DCM patients and evaluated their effects on NFAT lucifer...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Abraityte, Aurelija, Lunde, Ida G., Askevold, Erik T., Michelsen, Annika E., Christensen, Geir, Aukrust, Pål, Yndestad, Arne, Fiane, Arnt, Andreassen, Arne, Aakhus, Svend, Dahl, Christen P., Gullestad, Lars, Broch, Kaspar, Ueland, Thor
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471231/
https://ncbi.nlm.nih.gov/pubmed/28615692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03625-9
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