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The origin of 15R-prostaglandins in the Caribbean coral Plexaura homomalla: Molecular cloning and expression of a novel cyclooxygenase

The highest concentrations of prostaglandins in nature are found in the Caribbean gorgonian Plexaura homomalla. Depending on its geographical location, this coral contains prostaglandins with typical mammalian stereochemistry (15S-hydroxy) or the unusual 15R-prostaglandins. Their metabolic origin ha...

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Bibliografiske detaljer
Main Authors: Valmsen, Karin, Järving, Ivar, Boeglin, William E., Varvas, Külliki, Koljak, Reet, Pehk, Tõnis, Brash, Alan R., Samel, Nigulas
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC35405/
https://ncbi.nlm.nih.gov/pubmed/11427702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.131022398
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