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Downregulation of the Mitochondrial Calcium Uniporter by Cancer-Related miR-25
The recently discovered mitochondrial calcium uniporter (MCU) promotes Ca(2+) accumulation into the mitochondrial matrix [1, 2]. We identified in silico miR-25 as a cancer-related MCU-targeting microRNA family and demonstrate that its overexpression in HeLa cells drastically reduces MCU levels and m...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3540261/ https://ncbi.nlm.nih.gov/pubmed/23246404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.11.026 |
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