Low CSF Levels of Both α-Synuclein and the α-Synuclein Cleaving Enzyme Neurosin in Patients with Synucleinopathy

Neurosin is a protease that in vitro degrades α-synuclein, the main constituent of Lewy bodies found in brains of patients with synucleinopathy including Parkinson's disease (PD) and dementia with Lewy bodies (DLB). Several studies have reported reduced cerebrospinal fluid (CSF) levels of α-syn...

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Bibliographic Details
Main Authors: Wennström, Malin, Surova, Yulia, Hall, Sara, Nilsson, Christer, Minthon, Lennart, Boström, Fredrik, Hansson, Oskar, Nielsen, Henrietta M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540093/
https://ncbi.nlm.nih.gov/pubmed/23308173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053250
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