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Quantitative Imaging of Mitochondrial and Cytosolic Free Zinc Levels in an in vitro Model of Ischemia/Reperfusion

The role of zinc ion in cytotoxicity following ischemic stroke, prolonged status epilepticus, and traumatic brain injury remains controversial, but likely is the result of mitochondrial dysfunction. We describe an excitation ratiometric fluorescence biosensor based on human carbonic anhydrase II var...

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Autors principals: McCranor, Bryan J., Bozym, Rebecca A., Vitolo, Michele I., Fierke, Carol A., Bambrick, Linda, Polster, Brian M., Fiskum, Gary, Thompson, Richard B.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539817/
https://ncbi.nlm.nih.gov/pubmed/22430627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10863-012-9427-2
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