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α4β2 Nicotinic Acetylcholine Receptors on Dopaminergic Neurons Mediate Nicotine Reward and Anxiety Relief

Nicotine is the primary psychoactive substance in tobacco, and it exerts its effects by interaction with various subtypes of nicotinic acetylcholine receptors (nAChRs) in the brain. One of the major subtypes expressed in brain, the α4β2-nAChR, endogenously modulates neuronal excitability and thereby...

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Bibliographische Detailangaben
Hauptverfasser: McGranahan, Tresa M., Patzlaff, Natalie E., Grady, Sharon R., Heinemann, Stephen F., Booker, T. K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539812/
https://ncbi.nlm.nih.gov/pubmed/21795541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0937-11.2011
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