α4β2 Nicotinic Acetylcholine Receptors on Dopaminergic Neurons Mediate Nicotine Reward and Anxiety Relief

Nicotine is the primary psychoactive substance in tobacco, and it exerts its effects by interaction with various subtypes of nicotinic acetylcholine receptors (nAChRs) in the brain. One of the major subtypes expressed in brain, the α4β2-nAChR, endogenously modulates neuronal excitability and thereby...

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Detalhes bibliográficos
Main Authors: McGranahan, Tresa M., Patzlaff, Natalie E., Grady, Sharon R., Heinemann, Stephen F., Booker, T. K.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539812/
https://ncbi.nlm.nih.gov/pubmed/21795541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0937-11.2011
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