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An investigation on stereospecific fluorination at the 2′-arabino-position of a pyrimidine nucleoside: radiosynthesis of 2′-deoxy-2′-[(18)F]fluoro-5-methyl-1-β-D-arabinofuranosyluracil
Direct fluorination at the 2′-arabino-position of a pyrimidine nucleoside has been a long-standing challenge, yet we recently reported such a stereospecific fluorination for the first time in the synthesis of [(18)F]FMAU, albeit in low yields. Herein we report the results of an investigation on ster...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3539786/ https://ncbi.nlm.nih.gov/pubmed/23316091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2012.10.001 |
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