Crystallization and preliminary X-ray diffraction studies of Drosophila melanogaster Gαo-subunit of heterotrimeric G protein in complex with the RGS domain of CG5036

Regulator of G-protein signalling (RGS) proteins negatively regulate heterotrimeric G-protein signalling through their conserved RGS domains. RGS domains act as GTPase-activating proteins, accelerating the GTP hydrolysis rate of the activated form of Gα-subunits. Although omnipresent in eukaryotes,...

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Bibliographic Details
Main Authors: Tishchenko, Svetlana, Gabdulkhakov, Azat, Tin, Uliana, Kostareva, Olga, Lin, Chen, Katanaev, Vladimir L.
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2012
Subjects:
Crystallization Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539706/
https://ncbi.nlm.nih.gov/pubmed/23295489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S174430911204804X
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