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Overexpression, crystallization and preliminary X-ray crystallographic analysis of the phosphotriesterase from Mycobacterium tuberculosis

Organophosphates (OPs) are extremely toxic compounds that are used as insecticides or even as chemical warfare agents. Phosphotriesterases (PHPs) are responsible for the detoxification of OPs by catalysing their degradation. Almost 100 PHP structures have been solved to date, yet the crystal structu...

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Autors principals: Zhang, Liang, Chen, Ruyi, Dong, Zhe, Li, Xin
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539705/
https://ncbi.nlm.nih.gov/pubmed/23295488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112049032
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