IL-33 induces a hypo-responsive phenotype in human and mouse mast cells

IL-33 is elevated in afflicted tissues of patients with mast cell-dependent chronic allergic diseases. Based on its acute effects on mouse mast cells (MCs), IL-33 is thought to play a role in the pathogenesis of allergic disease through MC activation. However, the manifestations of prolonged IL-33 e...

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Detalhes bibliográficos
Main Authors: Jung, Mi-Yeon, Smrž, Daniel, Desai, Avanti, Bandara, Geethani, Ito, Tomonobu, Iwaki, Shoko, Kang, Jeong-Han, Andrade, Marcus V., Hilderbrand, Susana C., Brown, Jared M., Beaven, Michael A., Metcalfe, Dean D., Gilfillan, Alasdair M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538948/
https://ncbi.nlm.nih.gov/pubmed/23248261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201576
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