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Interplay of Priors and Skeletons in Two-Stage Continual Reassessment Method
Model based dose finding designs such as the Continual Reassessment Method (CRM), rely on some basic working model. In the Bayesian setting, these take the form of “guess estimates” of the probabilities of toxicity at each level. In the Likelihood setting, these estimates simply take the form of a m...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3538840/ https://ncbi.nlm.nih.gov/pubmed/22893483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.5559 |
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