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Thermal Stability of Fibroblast Growth Factor Protein Is a Determinant Factor in Regulating Self-Renewal, Differentiation, and Reprogramming in Human Pluripotent Stem Cells

Fibroblast growth factor (FGF), transforming growth factor (TGF)/Nodal, and Insulin/insulin-like growth factor (IGF) signaling pathways are sufficient to maintain human embryonic stem cells (ESCs) and induced pluripotent stem cells in a proliferative, undifferentiated state. Here, we show that only...

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Detalhes bibliográficos
Main Authors: Chen, Guokai, Gulbranson, Daniel R., Yu, Pengzhi, Hou, Zhonggang, Thomson, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538808/
https://ncbi.nlm.nih.gov/pubmed/22213113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1021
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