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Metabolic Regulation in Pluripotent Stem Cells during Reprogramming and Self-Renewal

Small, rapidly dividing pluripotent stem cells (PSCs) have unique energetic and biosynthetic demands compared with typically larger, quiescent differentiated cells. Shifts between glycolysis and oxidative phosphorylation with PSC differentiation or reprogramming to pluripotency are accompanied by ch...

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Bibliographic Details
Main Authors: Zhang, Jin, Nuebel, Esther, Daley, George Q., Koehler, Carla M., Teitell, Michael A.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492890/
https://ncbi.nlm.nih.gov/pubmed/23122286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.10.005
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