Reduced Cardiac Fructose 2,6 Bisphosphate Increases Hypertrophy and Decreases Glycolysis following Aortic Constriction

This study was designed to test whether reduced levels of cardiac fructose-2,6-bisphosphate (F-2,6-P(2)) exacerbates cardiac damage in response to pressure overload. F-2,6-P(2) is a positive regulator of the glycolytic enzyme phosphofructokinase. Normal and Mb transgenic mice were subject to transve...

Full description

Saved in:
Bibliographic Details
Main Authors: Wang, Jianxun, Xu, Jianxiang, Wang, Qianwen, Brainard, Robert E., Watson, Lewis J., Jones, Steven P., Epstein, Paul N.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538739/
https://ncbi.nlm.nih.gov/pubmed/23308291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053951
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items