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Vanadate raises fructose 2,6-bisphosphate concentrations and activates glycolysis in rat hepatocytes.

In rat hepatocytes, vanadate increases fructose 2,6-bisphosphate (Fru-2,6-P2) in a time- and dose-dependent manner, and counteracts the decrease in this metabolite caused by glucagon, forskolin or exogenous cyclic AMP. Vanadate does not directly modify the activity of 6-phosphofructo-2-kinase, even...

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Main Authors: Gómez-Foix, A M, Rodríguez-Gil, J E, Fillat, C, Guinovart, J J, Bosch, F
格式: Artigo
語言:Inglês
出版: 1988
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1135257/
https://ncbi.nlm.nih.gov/pubmed/2849417
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