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Load Regulates Bone Formation and Sclerostin Expression through a TGFβ-Dependent Mechanism

Bone continually adapts to meet changing physical and biological demands. Osteoblasts, osteoclasts, and osteocytes cooperate to integrate these physical and biochemical cues to maintain bone homeostasis. Although TGFβ acts on all three of these cell types to maintain bone homeostasis, the extent to...

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Bibliographische Detailangaben
Hauptverfasser: Nguyen, Jacqueline, Tang, Simon Y., Nguyen, Daniel, Alliston, Tamara
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538690/
https://ncbi.nlm.nih.gov/pubmed/23308287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053813
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