The DNA Copy Number of Human Endogenous Retrovirus-W (MSRV-Type) Is Increased in Multiple Sclerosis Patients and Is Influenced by Gender and Disease Severity

BACKGROUND: Multiple Sclerosis is an autoimmune disease more prevalent in women than in men. Multiple Sclerosis Associated Retrovirus element (MSRV) is a member of type-W endogenous retrovirus family (HERV-W), known to be associated to MS. Most HERVs are unable to replicate but MSRV expression assoc...

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Detalhes bibliográficos
Main Authors: Garcia-Montojo, Marta, Dominguez-Mozo, María, Arias-Leal, Ana, Garcia-Martinez, Ángel, De las Heras, Virginia, Casanova, Ignacio, Faucard, Raphaël, Gehin, Nadège, Madeira, Alexandra, Arroyo, Rafael, Curtin, François, Alvarez-Lafuente, Roberto, Perron, Hervé
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538585/
https://ncbi.nlm.nih.gov/pubmed/23308264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053623
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