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A lactate dehydrogenase ELISA-based assay for the in vitro determination of Plasmodium berghei sensitivity to anti-malarial drugs

BACKGROUND: Plasmodium berghei rodent malaria is a well-known model for the investigation of anti-malarial drug efficacy in vivo. However, the availability of drug in vitro assays in P. berghei is reduced when compared with the spectrum of techniques existing for Plasmodium falciparum. New alternati...

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Main Authors: Orjuela-Sánchez, Pamela, Duggan, Erika, Nolan, John, Frangos, John A, Carvalho, Leonardo JM
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538577/
https://ncbi.nlm.nih.gov/pubmed/23126583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-366
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