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New phosphine-diamine and phosphine-amino-alcohol tridentate ligands for ruthenium catalysed enantioselective hydrogenation of ketones and a concise lactone synthesis enabled by asymmetric reduction of cyano-ketones

Enantioselective hydrogenation of ketones is a key reaction in organic chemistry. In the past, we have attempted to deal with some unsolved challenges in this arena by introducing chiral tridentate phosphine-diamine/Ru catalysts. New catalysts and new applications are presented here, including the s...

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Hlavní autoři: Fuentes, José A, Phillips, Scott D, Clarke, Matthew L
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538564/
https://ncbi.nlm.nih.gov/pubmed/23216944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-153X-6-151
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