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M89V Sialic Acid Acetyl Esterase (SIAE) and All Other Non-Synonymous Common Variants of This Gene Are Catalytically Normal

Catalytically defective rare variants of Sialic acid Acetyl Esterase (SIAE) have previously been linked to autoimmunity. Studies presented here confirm that the M89V SIAE protein and all other products of common variant alleles of SIAE are catalytically normal. Although overexpressing transfected no...

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Detalhes bibliográficos
Main Authors: Chellappa, Vasant, Taylor, Kendra N., Pedrick, Kathryn, Donado, Carlos, Netravali, Ilka Arun, Haider, Khaleda, Cariappa, Annaiah, Dalomba, Natasha F., Pillai, Shiv
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538537/
https://ncbi.nlm.nih.gov/pubmed/23308225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053453
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