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Sox2(+) adult stem/progenitor cells are important for tissue regeneration and survival of mice

The transcription factor Sox2 maintains the pluripotency of early embryonic cells and regulates the formation of several epithelia during fetal development. Whether Sox2 continues to play a role in adult tissues remains largely unknown. We here show that Sox2 marks adult cells in several epithelial...

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Bibliografiska uppgifter
Huvudupphovsmän: Arnold, Katrin, Sarkar, Abby, Yram, Mary Anna, Polo, Jose M., Bronson, Rod, Sengupta, Sumitra, Seandel, Marco, Geijsen, Niels, Hochedlinger, Konrad
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538360/
https://ncbi.nlm.nih.gov/pubmed/21982232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2011.09.001
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