Transgenic Mice Overexpressing Renin Exhibit Glucose Intolerance and Diet-Genotype Interactions

Numerous animal and clinical investigations have pointed to a potential role of the renin-angiotensin system (RAS) in the development of insulin resistance and diabetes in conditions of expanded fat mass. However, the mechanisms underlying this association remain unclear. We used a transgenic mouse...

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Главные авторы: Fletcher, Sarah J., Kalupahana, Nishan S., Soltani-Bejnood, Morvarid, Kim, Jung Han, Saxton, Arnold M., Wasserman, David H., De Taeye, Bart, Voy, Brynn H., Quignard-Boulange, Annie, Moustaid-Moussa, Naima
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2013
Предметы:
Endocrinology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538348/
https://ncbi.nlm.nih.gov/pubmed/23308073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2012.00166
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