Overproduction of Angiotensinogen from adipose Tissue Induces adipose Infammation, Glucose Intolerance, and Insulin Resistance

Although obesity is associated with overactivation of the white adipose tissue (WAT) renin–angiotensin system (RAS), a causal link between the latter and systemic insulin resistance is not established. We tested the hypothesis that overexpression of angiotensinogen (Agt) from WAT causes systemic ins...

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Bibliographic Details
Published in:Obesity (Silver Spring)
Main Authors: Kalupahana, Nishan S., Massiera, Florence, Quignard-Boulange, Annie, Ailhaud, Gérard, Voy, Brynn H., Wasserman, David H., Moustaid-Moussa, Naima
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465436/
https://ncbi.nlm.nih.gov/pubmed/21979391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oby.2011.299
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