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Displaying High-affinity Ligands on Adeno-associated Viral Vectors Enables Tumor Cell-specific and Safe Gene Transfer

Gene transfer vectors derived from the adeno-associated virus (AAV) have recently received increasing attention due to substantial therapeutic benefit in several clinical trials. Nevertheless, their great potential for in vivo gene therapy can only be partially exploited owing to their broad tropism...

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Detalles Bibliográficos
Main Authors: Münch, Robert C, Janicki, Hanna, Völker, Iris, Rasbach, Anke, Hallek, Michael, Büning, Hildegard, Buchholz, Christian J
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538307/
https://ncbi.nlm.nih.gov/pubmed/22968478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.186
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