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Complete mitochondrial DNA genome sequence variation of Chinese families with mutation m.3635G>A and Leber hereditary optic neuropathy

PURPOSE: The majority of Leber hereditary optic neuropathy (LHON) cases are caused by one of three mitochondrial DNA (mtDNA) primary mutations (m.3460G>A, m.11778G>A, and m.14484T>C). In recent studies, we and others have shown that mutation m.3635G>A is a primary LHON mutation, particul...

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Autori principali: Bi, Rui, Zhang, A-Mei, Jia, Xiaoyun, Zhang, Qingjiong, Yao, Yong-Gang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Molecular Vision 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538042/
https://ncbi.nlm.nih.gov/pubmed/23304069
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