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Mitochondrial DNA Variation of Leber’s Hereditary Optic Neuropathy in Western Siberia

Our data first represent the variety of Leber’s hereditary optic neuropathy (LHON) mutations in Western Siberia. LHON is a disorder caused by pathogenic mutations in the mitochondrial DNA (mtDNA), inherited maternally and presents mainly in young adults, predominantly males. Clinically, LHON manifes...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cells
Auteurs principaux: Starikovskaya, Elena, Shalaurova, Sofia, Dryomov, Stanislav, Nazhmidenova, Azhar, Volodko, Natalia, Bychkov, Igor, Mazunin, Ilia, Sukernik, Rem
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6953113/
https://ncbi.nlm.nih.gov/pubmed/31817256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8121574
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