Diphtheria Toxin-Epidermal Growth Factor Fusion Protein DAB(389)EGF for the treatment of bladder cancer

PURPOSE: The novel fusion protein, DAB(389)EGF, is comprised of both the catalytic and translocation domains of diphtheria toxin that are fused to the human epidermal growth factor, providing a targeting and a toxicity component. We tested DAB(389)EGF for anti-tumor activity in both in vitro and in...

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Autors principals: Yang, Xiaoping, Kessler, Elizabeth, Su, Lih-Jen, Thorburn, Andrew, Frankel, Arthur E., Li, Yuan, La Rosa, Francisco G., Shen, Jingping, Li, Chuan-Yuan, Varella-Garcia, Marileila, Glodé, L. Michael, Flaig, Thomas W.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537889/
https://ncbi.nlm.nih.gov/pubmed/23172881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-1258
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