Targeting Truncated Retinoid X Receptor-α by CF31 induces TNFα-dependent apoptosis

A truncated version of retinoid X receptor-α, tRXRα, promotes cancer cell survival by activating the PI3K/AKT pathway. However, targeting the tRXRα-mediated survival pathway for cancer treatment remains to be explored. We report here our identification of a new natural product molecule, CF31, a xant...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wang, Guang-hui, Jiang, Fu-quan, Duan, Ying-hui, Zeng, Zhi-ping, Chen, Fan, Dai, Yi, Chen, Jie-bo, Liu, Jinxing, Liu, Jie, Zhou, Hu, Chen, Hai-feng, Zeng, Jin-zhang, Su, Ying, Yao, Xin-sheng, Zhang, Xiao-kun
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537848/
https://ncbi.nlm.nih.gov/pubmed/23151904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-2038
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados