Regulation of proteolytic cleavage of retinoid X receptor-α by GSK-3β

We recently reported that an N-terminally truncated retinoid X receptor-α (tRXRα) produced in cancer cells acts to promote cancer cell growth and survival through AKT activation. However, how RXRα is cleaved and how the cleavage is regulated in cancer cells remain undefined. In this study, we demons...

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Detalhes bibliográficos
Main Authors: Gao, Weiwei, Liu, Jie, Hu, Mengjie, Huang, Mingfeng, Cai, Sisi, Zeng, Zhiping, Lin, Bingzhen, Cao, Xihua, Chen, Jiebo, Zeng, Jin-zhang, Zhou, Hu, Zhang, Xiao-kun
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
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Original Manuscript
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670254/
https://ncbi.nlm.nih.gov/pubmed/23389291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt043
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