Regulation of proteolytic cleavage of retinoid X receptor-α by GSK-3β

We recently reported that an N-terminally truncated retinoid X receptor-α (tRXRα) produced in cancer cells acts to promote cancer cell growth and survival through AKT activation. However, how RXRα is cleaved and how the cleavage is regulated in cancer cells remain undefined. In this study, we demons...

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Main Authors: Gao, Weiwei, Liu, Jie, Hu, Mengjie, Huang, Mingfeng, Cai, Sisi, Zeng, Zhiping, Lin, Bingzhen, Cao, Xihua, Chen, Jiebo, Zeng, Jin-zhang, Zhou, Hu, Zhang, Xiao-kun
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2013
Ábhair:
Original Manuscript
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670254/
https://ncbi.nlm.nih.gov/pubmed/23389291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt043
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