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gp96 expression in neutrophils is critical for the onset of Escherichia coli K1 (RS218) meningitis

Despite the fundamental function of neutrophils (PMNs) in innate immunity, their role in Escherichia coli K1 (EC-K1) induced meningitis is unexplored. Here we show that PMN-depleted mice are resistant to EC-K1 (RS218) meningitis. EC-K1 survives and multiplies in PMNs for which outer membrane protein...

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Sonraí Bibleagrafaíochta
Main Authors: Mittal, Rahul, Prasadarao, Nemani V.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537828/
https://ncbi.nlm.nih.gov/pubmed/22109526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1554
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