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Inhibition of Inducible Nitric Oxide Controls Pathogen Load and Brain Damage by Enhancing Phagocytosis of Escherichia coli K1 in Neonatal Meningitis

Escherichia coli K1 is a leading cause of neonatal meningitis in humans. In this study, we sought to determine the pathophysiologic relevance of inducible nitric oxide (iNOS) in experimental E. coli K1 meningitis. By using a newborn mouse model of meningitis, we demonstrate that E. coli infection tr...

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Bibliografski detalji
Glavni autori: Mittal, Rahul, Gonzalez-Gomez, Ignacio, Goth, Kerstin A., Prasadarao, Nemani V.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832150/
https://ncbi.nlm.nih.gov/pubmed/20093483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090851
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