Effective Preparation of Plasmodium vivax Field Isolates for High-Throughput Whole Genome Sequencing

Whole genome sequencing (WGS) of Plasmodium vivax is problematic due to the reliance on clinical isolates which are generally low in parasitaemia and sample volume. Furthermore, clinical isolates contain a significant contaminating background of host DNA which confounds efforts to map short read seq...

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Autores principales: Auburn, Sarah, Marfurt, Jutta, Maslen, Gareth, Campino, Susana, Ruano Rubio, Valentin, Manske, Magnus, MacHunter, Barbara, Kenangalem, Enny, Noviyanti, Rintis, Trianty, Leily, Sebayang, Boni, Wirjanata, Grennady, Sriprawat, Kanlaya, Alcock, Daniel, MacInnis, Bronwyn, Miotto, Olivo, Clark, Taane G., Russell, Bruce, Anstey, Nicholas M., Nosten, François, Kwiatkowski, Dominic P., Price, Ric N.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537768/
https://ncbi.nlm.nih.gov/pubmed/23308154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053160
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