An inverse metabolic engineering approach for the design of an improved host platform for over-expression of recombinant proteins in Escherichia coli

BACKGROUND: A useful goal for metabolic engineering would be to generate non-growing but metabolically active quiescent cells which would divert the metabolic fluxes towards product formation rather than growth. However, for products like recombinant proteins, which are intricately coupled to the gr...

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Hlavní autoři: Ghosh, Chaitali, Gupta, Rashmi, Mukherjee, Krishna Jyoti
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537655/
https://ncbi.nlm.nih.gov/pubmed/22759404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-11-93
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