Human Cytomegalovirus Interleukin-10 Downregulates Metalloproteinase Activity and Impairs Endothelial Cell Migration and Placental Cytotrophoblast Invasiveness In Vitro

At the uterine-placental interface, fetal cytotrophoblasts invade the decidua, breach maternal blood vessels, and form heterotypic contacts with uterine microvascular endothelial cells. In early gestation, differentiating- invading cytotrophoblasts produce high levels of matrix metalloproteinase 9 (...

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Pubblicato in:	J Virol
Autori principali:	Yamamoto-Tabata, Takako, McDonagh, Susan, Chang, Hsin-Ti, Fisher, Susan, Pereira, Lenore
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2004
Soggetti:	Pathogenesis and Immunity
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC353759/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14990702/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.6.2831-2840.2004
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