Human Cytomegalovirus Interleukin-10 Downregulates Metalloproteinase Activity and Impairs Endothelial Cell Migration and Placental Cytotrophoblast Invasiveness In Vitro

At the uterine-placental interface, fetal cytotrophoblasts invade the decidua, breach maternal blood vessels, and form heterotypic contacts with uterine microvascular endothelial cells. In early gestation, differentiating- invading cytotrophoblasts produce high levels of matrix metalloproteinase 9 (...

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Autori principali: Yamamoto-Tabata, Takako, McDonagh, Susan, Chang, Hsin-Ti, Fisher, Susan, Pereira, Lenore
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC353759/
https://ncbi.nlm.nih.gov/pubmed/14990702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.6.2831-2840.2004
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