Cul7/p185/p193 Binding to Simian Virus 40 Large T Antigen Has a Role in Cellular Transformation

Simian virus 40 large T antigen (TAg) is a viral oncoprotein that can promote cellular transformation. TAg's transforming activity results in part by binding and inactivating key tumor suppressors, including p53 and the retinoblastoma protein (pRb). We have identified a TAg-associated 185-kDa p...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Ali, Syed Hamid, Kasper, Jocelyn S., Arai, Takehiro, DeCaprio, James A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2004
Soggetti:
Transformation and Oncogenesis
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC353757/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14990695/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.6.2749-2757.2004
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