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Reduced cul-5 activity causes aberrant follicular morphogenesis and germ cell loss in Drosophila oogenesis.

Drosophila oogenesis is especially well suited for studying stem cell biology, cellular differentiation, and morphogenesis. The small modifier protein ubiquitin regulates many cellular pathways. Ubiquitin is conjugated to target proteins by a diverse class of enzymes called ubiquitin E3 ligases. Her...

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Detalles Bibliográficos
Principais autores: Jan-Michael Kugler, Christopher Lem, Paul Lasko
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2010-02-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC2816211?pdf=render
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