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BATF-JUN is critical for IRF4-mediated transcription in T cells
Interferon regulatory factor 4 (IRF4) is an IRF family transcription factor with critical roles in lymphoid development and in regulating the immune response(1,2). IRF4 binds DNA weakly due to a C-terminal auto-inhibitory domain, but cooperative binding with factors such as PU.1 or SPIB in B cells i...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3537508/ https://ncbi.nlm.nih.gov/pubmed/22992523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11530 |
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