Endothelin-A Receptor Antagonism Modifies Cardiovascular Risk Factors in CKD

Arterial stiffness and impaired nitric oxide (NO) bioavailability contribute to the high risk for cardiovascular disease in CKD. Both asymmetric dimethylarginine (ADMA), an endogenous inhibitor of NO production, and endothelin-1 (ET-1) oppose the actions of NO, suggesting that ET-1 receptor antagoni...

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Detaylı Bibliyografya
Asıl Yazarlar: Dhaun, Neeraj, Melville, Vanessa, Blackwell, Scott, Talwar, Dinesh K., Johnston, Neil R., Goddard, Jane, Webb, David J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Nephrology 2012
Konular:
Brief Communication
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537212/
https://ncbi.nlm.nih.gov/pubmed/23243212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012040355
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