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Neurokinin-1 Receptor Directly Mediates Glioma Cell Migration by Up-regulation of Matrix Metalloproteinase-2 (MMP-2) and Membrane Type 1-Matrix Metalloproteinase (MT1-MMP)

Neurokinin-1 receptor (NK1R) occurs naturally on human glioblastomas. Its activation mediates glioma cell proliferation. However, it is unknown whether NK1R is directly involved in tumor cell migration. In this study, we found human hemokinin-1 (hHK-1), via NK1R, dose-dependently promoted the migrat...

詳細記述

保存先:
書誌詳細
主要な著者: Mou, Lingyun, Kang, Yawei, Zhou, Ying, Zeng, Qian, Song, Hongjing, Wang, Rui
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537028/
https://ncbi.nlm.nih.gov/pubmed/23166329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.389783
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