Phosphorylation of Dopamine Transporter Serine 7 Modulates Cocaine Analog Binding

As an approach to elucidating dopamine transporter (DAT) phosphorylation characteristics, we examined in vitro phosphorylation of a recombinant rat DAT N-terminal peptide (NDAT) using purified protein kinases. We found that NDAT becomes phosphorylated at single distinct sites by protein kinase A (Se...

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Main Authors: Moritz, Amy E., Foster, James D., Gorentla, Balachandra K., Mazei-Robison, Michelle S., Yang, Jae-Won, Sitte, Harald H., Blakely, Randy D., Vaughan, Roxanne A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Neurobiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537014/
https://ncbi.nlm.nih.gov/pubmed/23161550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.407874
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