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Acute β-Adrenergic Activation Triggers Nuclear Import of Histone Deacetylase 5 and Delays G(q)-induced Transcriptional Activation
During hemodynamic stress, catecholamines and neurohumoral stimuli may induce co-activation of G(q)-coupled receptors and β-adrenergic receptors (β-AR), leading to cardiac remodeling. Dynamic regulation of histone deacetylase 5 (HDAC5), a transcriptional repressor, is crucial during stress signaling...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3537013/ https://ncbi.nlm.nih.gov/pubmed/23161540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.382358 |
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