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Promiscuous Dimerization of the Growth Hormone Secretagogue Receptor (GHS-R1a) Attenuates Ghrelin-mediated Signaling

G protein-coupled receptors (GPCRs), such as the ghrelin receptor (GHS-R1a), the melanocortin 3 receptor (MC(3)), and the serotonin 2C receptor (5-HT(2C)), are well known for their key role in the homeostatic control of food intake and energy balance. Ghrelin is the only known gut peptide exerting a...

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Detalhes bibliográficos
Main Authors: Schellekens, Harriët, van Oeffelen, Wesley E. P. A., Dinan, Timothy G., Cryan, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537012/
https://ncbi.nlm.nih.gov/pubmed/23161547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.382473
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