Dual Function of Mitochondrial Nm23-H4 Protein in Phosphotransfer and Intermembrane Lipid Transfer: A CARDIOLIPIN-DEPENDENT SWITCH

The nucleoside diphosphate kinase Nm23-H4/NDPK-D forms symmetrical hexameric complexes in the mitochondrial intermembrane space with phosphotransfer activity using mitochondrial ATP to regenerate nucleoside triphosphates. We demonstrate the complex formation between Nm23-H4 and mitochondrial GTPase...

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Detalhes bibliográficos
Main Authors: Schlattner, Uwe, Tokarska-Schlattner, Malgorzata, Ramirez, Sacnicte, Tyurina, Yulia Y., Amoscato, Andrew A., Mohammadyani, Dariush, Huang, Zhentai, Jiang, Jianfei, Yanamala, Naveena, Seffouh, Amal, Boissan, Mathieu, Epand, Raquel F., Epand, Richard M., Klein-Seetharaman, Judith, Lacombe, Marie-Lise, Kagan, Valerian E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Membrane Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537004/
https://ncbi.nlm.nih.gov/pubmed/23150663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.408633
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