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Adaptive changes of human islets to an obesogenic environment in the mouse
AIMS/HYPOTHESIS: In this study, we used an immunodeficient mouse model to explore, in vivo, the longitudinal adaptation of human islets to an obesogenic environment. METHODS: Non-diabetic Rag2 (–/–) mice (n = 61) were transplanted with human islets (400 islet equivalents [IEQ]) from six pancreases:...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Springer-Verlag
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3536990/ https://ncbi.nlm.nih.gov/pubmed/23192693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-012-2775-y |
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