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A Critical Assessment of Feature Selection Methods for Biomarker Discovery in Clinical Proteomics

In this paper, we compare the performance of six different feature selection methods for LC-MS-based proteomics and metabolomics biomarker discovery—t test, the Mann–Whitney–Wilcoxon test (mww test), nearest shrunken centroid (NSC), linear support vector machine–recursive features elimination (SVM-R...

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Detalhes bibliográficos
Main Authors: Christin, Christin, Hoefsloot, Huub C. J., Smilde, Age K., Hoekman, B., Suits, Frank, Bischoff, Rainer, Horvatovich, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536906/
https://ncbi.nlm.nih.gov/pubmed/23115301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.022566
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