Attenuated Inflammatory Response in Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Knock-Out Mice following Stroke

BACKGROUND: Triggering receptor expressed on myeloid cells-2 (TREM2) is a microglial surface receptor involved in phagocytosis. Clearance of apoptotic debris after stroke represents an important mechanism to re-attain tissue homeostasis and thereby ensure functional recovery. The role of TREM2 follo...

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Main Authors: Sieber, Matthias W., Jaenisch, Nadine, Brehm, Martin, Guenther, Madlen, Linnartz-Gerlach, Bettina, Neumann, Harald, Witte, Otto W., Frahm, Christiane
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536811/
https://ncbi.nlm.nih.gov/pubmed/23301011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052982
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