Alternative Oxidase Expression in the Mouse Enables Bypassing Cytochrome c Oxidase Blockade and Limits Mitochondrial ROS Overproduction

Cyanide-resistant non-phosphorylating respiration is known in mitochondria from plants, fungi, and microorganisms but is absent in mammals. It results from the activity of an alternative oxidase (AOX) that conveys electrons directly from the respiratory chain (RC) ubiquinol pool to oxygen. AOX thus...

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Détails bibliographiques
Auteurs principaux: El-Khoury, Riyad, Dufour, Eric, Rak, Malgorzata, Ramanantsoa, Nelina, Grandchamp, Nicolas, Csaba, Zsolt, Duvillié, Bertrand, Bénit, Paule, Gallego, Jorge, Gressens, Pierre, Sarkis, Chamsy, Jacobs, Howard T., Rustin, Pierre
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536694/
https://ncbi.nlm.nih.gov/pubmed/23300486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003182
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